Thursday, October 17, 2019

Macroeconomics Problem Set 3 Assignment Example | Topics and Well Written Essays - 1250 words

Macroeconomics Problem Set 3 - Assignment Example d. What will the capital-output ratio be at the Golden Rule steady-state? (Hint: recall from Chapter 3 that for the Cobb-Douglas production function, the capital-output ratio is related to the marginal product of capital). 1. In this question, we examine how the goals of the Federal Reserve influence its response to shocks. Suppose that in scenario A, the Fed cares only about keeping the price level stable whereas in scenario B, the Fed cares only about keeping output and employment at their natural levels. Explain how in each scenario the Fed would respond to the following: A decrease in velocity causes a downward shift on the aggregate demand. Prices are fixed in the short run meaning only output decreases. To ensure output and unemployment are at their natural rates Fed B should increase the money supply to attain the initial equilibrium where prices and output will be constant. Fed, A should also increase the money supply to shift the aggregate demand curve upwards since this is the only way to ensure stable prices at their original equilibrium. This results to an upward shift of the supply curve. To ensure stable prices, Fed B should hold aggregate demand constant since prices will rise in the short run and then fall in the long run achieving the natural rate of unemployment. This might however result to a recession. To keep output and unemployment at their natural rate Fed B should increase the money supply hence shift the aggregate demand curve upwards. This results to a new equilibrium at higher prices, but there is no loss in output. Based on the quantity equation MV=PY, if Fed reduces the money supply by 5% the aggregate demand curve will shift downwards. A decrease in M will hence result in a decrease in PY provided V is constant. In the short run, the assumption is that the price levels are fixed meaning that that the aggregate

Creation Of Pakistan Essay Example | Topics and Well Written Essays - 1250 words - 5

Creation Of Pakistan - Essay Example On June 23, 1947, the partition of the subcontinent was announced by the British. It was then that the foundation of a new Islamic state named Pakistan was laid. This was considered to be a practical initiation of the creation of a brand new nation, whose values were laid on strong norms and beliefs. Pakistan’s Independence Day is celebrated on August 14 every year. This day is actually considered to be the celebration of the announcement of a country coming into being. The creation of Pakistan was not merely an idea. It, however, came into being when the first Muslim stepped on this piece of land. The independence day of Pakistan is celebrated on a grand scale by its citizens. The whole nation on this particular day shares the spirit of brotherhood, unity, serenity, comradeship and global peace. People must understand that the creation of Pakistan was not lesser than a miracle. It was the creation of the land where religions like Hinduism and Buddhism were rooted for thousand s of years. People didn’t even imagine that it is possible to conquer such a piece of land for the purpose of implementing the principles and teachings of Islam. It was in the 18th century when the people of the Arab countries including the Muslims were contributing their parts to flourish trade between different countries. It was then that the detention of a Muslim lady had been reported to Hajjaj Bin Youssef who was a great Muslim leader. He then sent a nuke youngster almost 17 years old named Muhammad Bin Qasim to invade the land and acclimatize the detained Muslim lady. Muhammad Bin Qasim the great Islamic warrior invaded and defeated Raju Dahir with a limited army and captured the Port of Debal which is now known as Karachi. It was then that the Muslim scholars began to arrive at the subcontinent. This can be considered as a great breakthrough towards the creation of a separate homeland for Muslims.

Wednesday, October 16, 2019

Mass Spectrometry and HPLC of peptides Lab Report

Mass Spectrometry and HPLC of peptides - Lab Report Example The mass of the protonated and solvated molecules pass through the mass analyzer that establishes the mass of the analyte. Reversed phase high pressure liquid chromatography relies on the reversible water-hating associations between the molecules of the solute present in a polar mobile phase and the immobilised hydrophobic ligand in the solid support to effect separation (David 2001). The dispersal of the solute between the two phases is a function of the binding attributes of the medium, the polarity of the solute and the constituents of the mobile phase. The polarity of the mobile phase is lowered by the addition of organic solvents, which minimize the hydrophobic associations between the solute and the stationary phase hence causing desorption. Hydrophobic molecules end up spending more time on the solid support hence requiring a high solvent concentration to promote desorption. The mass to charge ratio (m/z) is the proportion of the mass of a substance to the number of ions present in a substance. This value is obtained sing the formula m/z = (MW + nH+)/n where m/z = the mass-to-charge ratio, which is indicated on the axis of the spectrum; MW is the molecular mass of the sample; n is the integer number of charges on the ions and H is the mass of a proton, which is equivalent to 1.008 Da. The above equation can be used to find the molecular weight of a sample provided that the sum of charges on an ion is established. The m/z value is read from the spectrum and substituted into the equation. Usually, during the calculation of charge, it is assumed that any two adjacent members in the sequence of multiplied charged ions differ by one charge. The mass of charge ratio (m/z) of large molecules such as ionised proteins, for example, lysozyme and bovine serum albumin is obtained in the same manner as described. The charge of the ion is found by monitoring adjacent charge states and substituted into the above equation alongside the m/z ratio that

Creation Of Pakistan Essay Example | Topics and Well Written Essays - 1250 words - 5

Creation Of Pakistan - Essay Example On June 23, 1947, the partition of the subcontinent was announced by the British. It was then that the foundation of a new Islamic state named Pakistan was laid. This was considered to be a practical initiation of the creation of a brand new nation, whose values were laid on strong norms and beliefs. Pakistan’s Independence Day is celebrated on August 14 every year. This day is actually considered to be the celebration of the announcement of a country coming into being. The creation of Pakistan was not merely an idea. It, however, came into being when the first Muslim stepped on this piece of land. The independence day of Pakistan is celebrated on a grand scale by its citizens. The whole nation on this particular day shares the spirit of brotherhood, unity, serenity, comradeship and global peace. People must understand that the creation of Pakistan was not lesser than a miracle. It was the creation of the land where religions like Hinduism and Buddhism were rooted for thousand s of years. People didn’t even imagine that it is possible to conquer such a piece of land for the purpose of implementing the principles and teachings of Islam. It was in the 18th century when the people of the Arab countries including the Muslims were contributing their parts to flourish trade between different countries. It was then that the detention of a Muslim lady had been reported to Hajjaj Bin Youssef who was a great Muslim leader. He then sent a nuke youngster almost 17 years old named Muhammad Bin Qasim to invade the land and acclimatize the detained Muslim lady. Muhammad Bin Qasim the great Islamic warrior invaded and defeated Raju Dahir with a limited army and captured the Port of Debal which is now known as Karachi. It was then that the Muslim scholars began to arrive at the subcontinent. This can be considered as a great breakthrough towards the creation of a separate homeland for Muslims.

Tuesday, October 15, 2019

The Essence of Love Essay Example for Free

The Essence of Love Essay The essence of love is an eternally controversial topic, the opinions of which vary from person to person. Some dont have sufficient faith in pure-love, on the contrary, others are firmly convinced that love is unconditional. From my perspective, love is as immaculate as snow that people yearn for, however to some extent, the material factor is supposed to be emphasized beyond reproach. What should be reached an absolute consensus is that genuine love cant depend on how much money he or she possesses, as the reason why you love him or her is relevant to nothing but the feeling when you get together. Your life can be perfect if you grow old with whom you love. When love comes to you, you can fly like an angel, living where full of brilliantly-colored and fragrant flowers. Nevertheless, coming back to earth, if you dont have money, how can your life be sustained? No one can deny that there is a common phenomenon in terms of love that many people divorce or lovers break up just due to economic reasons, like a tragedy. In the course of going in for eternal love, you may be in a dilemma that how to figure out the tricky and perplexing question which is more significant, the true love or the money? However, as a matter of fact, money is the base of our life, as correspond to love. What if you marry a person who is not your cup of tea?

Monday, October 14, 2019

Emetic and anti-emetic drugs

Emetic and anti-emetic drugs The Necessity Humans are fundamentally animals, and in true Darwinian fashion, survival is key. The process of emesis, or vomiting, can often be regarded as a defensive mechanism adopted by humans and other animals. One example of this is using emesis to reverse the potentially deadly mistake of eating a poisonous substance. If the bodies natural defences failed to recognise the danger of the foreign toxin in the blood stream, it may be essential to induce emesis. Hence, a need for emetic drugs arose, drugs which would stimulate the bodys natural defences and promote vomiting. However, not all vomiting is a defensive reflex, such as motion sickness, or the nausea associated with pregnancy, both of which cause no biological threat to the existence of the human. The extreme emesis suffered by chemotherapy patients is another strong cause for drugs to allow control over the vomiting process, and so the necessity for anti-emetic drugs also arose. The Emetic Response The act of emesis is in fact a fairly complex one, requiring the co-ordination of the somatic respiratory and abdominal muscles, and the muscles of the gastrointestinal tract. Two sections of the medulla function to regulate the event of emesis, the chemoreceptor trigger zone (CTZ) and the vomiting centre. The CTZ is located in the area postrema, on the floor of the fourth ventricle of the brain, and is sensitive to chemical stimuli present in the plasma. Many drugs can be used to counteract substances working on the CTZ, reaching the area of the brain via the blood stream. The blood-brain barrier around the CTZ is permeable, allowing drugs to act directly on it. The vomiting centre is, however, used to co-ordinate the actual event of emesis, regulating the movement of smooth and striated muscle. The CTZ transmits signals to the vomiting centre when a stimuli acts upon the CTZ, causing the activation of the emetic reflex. Emetic Drugs As previously stated, sometimes emesis is a desirable process, such as in the event of swallowing a toxic substance. It is also, perhaps [a bit irishly], necessary to promote vomiting in the test for anti-emetic drugs. The main emetic drug that is used is Ipecacuanha, which contains two substance, emetine and cephaeline, which irritate the gastrointestinal tract to cause the patient to vomit. However, migranes and indigestion are common side effects Motion Sickness Emesis can be induced without any influence from foreign substances within the body. Motion sickness is a prime example of this, and has no biological significance on the existence of humans. In the process of motion sickness, the labyrinth in the vestibular apparatus of the ear is moved in a certain way. This relays a signal to the floor of the fourth ventricle, but the mechanism of movement of the signal to the CTZ is yet unknown. It has been hypothesised that the cerebellum may possibly act as a second relay centre, but as the CTZ only responds to chemicals in the plasma, the synaptic pulses from the relay centres could not act directly upon it. However, although the mechanism of motion sickness is not yet fully known, many drugs for motion sickness have been designed, antagonising the H1 and muscarinic receptors. H1-receptor antagonists Histamine H1 receptor antagonists can prevent emesis by competing with histamine on the H1-receptor sites. The precise mechanism of action is yet unknown, but it has been thought that the administered antihistamine competitively blocks the H1-receptors of the vestibular apparatus, reducing sensitivity, and can act directly on the gut, which, in turn, relieves the vomiting associated with motion sickness. Furthermore, first-generation H1-receptor antagonist may also block the chemoreceptor trigger zone, and act on the nucleus of the solitary tract (brainstem) by crossing the blood-brain barrier, preventing vomiting in the patient. However, this treatment is mainly effective if administered before the onset of emesis, though may manage to help control emesis once it has began. As can be seem from the chemical structure opposite, the general structure of H1-receptor antagonists can be portrayed simply. Many first-generation antihistamines cause drowsiness as a very common side effect, d ue to the anticholinergic properties of the drug. However, this anticholinergic property can also act as an anti-emetic, making the first-generation antihistamine drugs more effective. Muscarinic-receptor antagonists Muscarinic receptor antagonists. Good for prevention of motion sickness. scopolamine (Transderm-Scop) Para4: (working on stomach) muscarinic receptor antagonist Side effects, ways it works, problems, structures, point out where it acts, and how the structure makes it act in that way. Explain how the drug interferes with the normal emesis process. Muscarinic-receptor antagonists (Chapter 7) Hyoscine active against nausea and vomiting caused by the stimuli of the labyrinth (ear), and against substances which act on the stomach directly, but not against things which act on the CTZ. (same as H1) Hyoscine is best agent for prevention of motion sickness, but less useful once sickness occurs. Effect peaks after 1-2 hours after ingestion, can also be given transdermally (via the skin like a nicotine patch), and is usually put behind the ear. Unwanted side effects: drowsiness, dry mouth. (other side effects can include blurring vision and retention of urine, but dont normally occur at the doses given for anti-emetic effects) Reference List: Hawthorn, Jan. Understanding and Management of Nausea and Vomiting, Blackwell Science, 1st Edition, 1995 Rang and Dale Bartholow, Roberts. Ipecacuanha, A Practical Treatise on Materia Medica and Therapeutics, Appleton and Company, 1908

Sunday, October 13, 2019

Analysis of I Heard a Fly Buzz When I Died and Because I Could Not Stop

Analysis of I Heard a Fly Buzz When I Died and Because I Could Not Stop for Death by Emily Dickinson Emily Dickinson wrote many poems in her lifetime. She writes two of my favorite poems. They are: ?I heard a Fly buzz when I died? and ?Because I could not stop for Death?. They both have similarities and differences from each other. There are similarities in these two poems such as the theme and the observentness of the narrator. Both of the poems themes involve death. In ?I heard a Fly buzz when I died?, the poet writes, ? And then the Windows failed ? and then I could not see to see- ", which means that the narrator?s eyes would not open no more; they had died. In ?Because I could not stop for Death? it shows the theme even in the title. In this poem, the poet writes in a clearer way that her theme was of a deathly tone. ?Because I could not stop for Death- He kindly stopped for me?. The narrator in these two poems is quiet observant. In ?I heard a Fly buzz when I died?, the narrator can hear the buzzing of a fly just before he/she dies. The poet writes, ?-a...